Histopathological findings in the iris of dapsone treated leprosy patients.

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Histopathological findings in the iris of dapsone treated leprosy patients.

From 43 Nepalese leprosy patients skin smear negative, and treated with dapsone (diamino diphenyl sulphone), and without any sign of active leprosy or iritis, specimens from iridectomy during cataract surgery were studied histopathologically. Of 49 iris specimens only six (12%) were found to be without any histopathological change. Atrophy of the iris stroma was seen in 63% and neovascularisati...

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The self-administration of dapsone by leprosy patients in Ethiopia.

In a second investigation of the regularity of dapsone self. administration among outpatients in Addis Ababa , the compliance of patients participating in a trial to assess the ability of combinations of dapsone, thiacetazone and rifampicin to prevent relapse with dapsone­ resistant leprosy was compared with that of non-trial patients. Despite the considerable additional time spent on encouragi...

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Malaria, leprosy and dapsone.

Although the preventive action of dapsone against P. falciparum malaria was known for many years, there was no report about the incidence of P. falciparum malaria in leprosy patients treated with dapsone, especially from areas of Southeast Asia where both leprosy and malaria are endemic. Therefore, two clinic-based malaria surveys were undertaken at a gap of 12 years, comprising 506 lepromatous...

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Self-administered dapsone compliance of leprosy patients in eastern Nepal.

Self-administered dapsone intake by leprosy patients in Eastern Nepal was monitored with a urine spot test. Of 341 outpatients 55 (16.1%) were found to be noncompliant. A significant relationship was found between noncompliance and age and between noncompliance and caste. Sex, disease classification, type of treatment, duration of treatment, history of leprosy reactions and travel time to the c...

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Dapsone hypersensitivity syndrome among leprosy patients in China.

OBJECTIVE To Study the incidence and clinical characteristics of dapsone hypersensitivity syndrome (DHS) among MDT-treated leprosy patients from 2006 to 2009 in China. METHODS A retrospective survey was carried out throughout China using a specially designed questionnaire. RESULTS From 2006 to 2009, there were 63 new patients reported to have DHS with an incidence of 1.0%. Among these patie...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 1990

ISSN: 0007-1161

DOI: 10.1136/bjo.74.1.14